Metronidazole-resistant Trichomonas vaginalis.
نویسندگان
چکیده
منابع مشابه
Metronidazole-resistant Trichomonas vaginalis.
A 36-year-old woman with symptomatic metronidazole-resistant trichomonal vaginitis for 10 years had a total of 22 courses of treatment with either metronidazole or tinidazole according to different schedules. The minimum trichomonicidal concentration of metronidazole for the strain of Trichomonas vaginalis isolated from the patient was 160 microgram/ml compared with 1.25-10 microgram/ml for oth...
متن کاملTreatment of infections caused by metronidazole-resistant Trichomonas vaginalis.
Infections with the sexually transmitted protozoan Trichomonas vaginalis are usually treated with metronidazole, a 5-nitroimidazole drug derived from the antibiotic azomycin. Metronidazole treatment is generally efficient in eliminating T. vaginalis infection and has a low risk of serious side effects. However, studies have shown that at least 5% of clinical cases of trichomoniasis are caused b...
متن کاملIn vitro metronidazole and tinidazole activities against metronidazole-resistant strains of Trichomonas vaginalis.
The in vitro activities of tinidazole and metronidazole against Trichomonas vaginalis isolates clinically resistant to metronidazole were compared. Minimal lethal concentrations (MLCs) of tinidazole were significantly lower than MLCs of metronidazole. Increased metronidazole resistance correlated with increased tinidazole resistance. These data support a role for tinidazole in the treatment of ...
متن کاملStudies on strain sensitivity of Trichomonas vaginalis to metronidazole.
Ninety-four strains of Trichomonas vaginalis isolated from unselected patients in Vienna during the period from November 1975 to November 1975 were subjected to sensitivity tests against metronidazole in vitro and in vivo. Nearly 90% of the isolates examined showed in vitro growth inhibition at concentrations of 0.4 to 1.6 microgram metronidazole/ml and only about 10% at concentrations of less ...
متن کاملFurther observations on strain sensitivity of Trichomonas vaginalis to metronidazole.
Squires and McFadzean (1962) reviewed the question of strain sensitivity of Trichomonas vaginalis to metronidazole. Since then examinations of the sensitivities of strains isolated from occasional patients who had apparently not responded to treatment with metronidazole have been continued. The results of these examinations are described. It was also thought worth while to examine the strain se...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1979
ISSN: 1368-4973
DOI: 10.1136/sti.55.5.351